Biopharmaceutical CMO and CRO Market Growth, Trends, Industry Statistics 2022-2030

The global biopharmaceutical CMO and CRO market size was valued at USD 30.1 billion in 2020, and is predicted to be worth around USD 60.1 billion by 2030, registering a CAGR of 7.6% during the forecast period 2022 to 2030.

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Growth Factors

There was unprecedented growth in 2020 due to the COVID-19 pandemic. The rising investments in the biopharmaceutical industry by the prominent participants to enhance their productivity and efficiency have driven the bio manufacturers to increase their focus on outsourcing activities. Currently, biopharma companies have begun outsourcing the resource and capital-intensive steps and, in a few cases, the entire chain of biomanufacturing, thereby boosting the demand for contract-based services.

The robustness of venture capital investments is one of the important supportive factors that has created opportunities for the growth of CMOs. Venture capital funds are considered more reliable than public equity. An increase in the availability of venture funds for life sciences is expected to bolster the growth of CMOs. However, these CMOs & CROs are expected to face competition from in-house departments of pharmaceutical & biotechnology companies. Several big pharma companies like Novartis announced to maintain and expand their biomanufacturing processes in-house over the coming years.

Report Coverage

Report Scope Details
Market Size US$ 60.1 billion by 2030
Growth Rate CAGR of 7.6% From 2022 to 2030
Largest Market North America
Base Year 2021
Forecast Period 2022 to 2030
Segments Covered Source, Service, Product
Regional Scope North America, Europe, Asia Pacific, Latin America, Middle East & Africa
Companies Mentioned Boehringer Ingelheim GmbH; Lonza Group AG; Inno Biologics Sdn Bhd; Rentschler Biopharma SE; JRS Pharma; Biomeva GmbH; ProBioGen AG; Fujifilm Diosynth Biotechnologies U.S.A., Inc.; Toyobo Co., Ltd.; Samsung Biologics

By Source Analysis

The mammalian segment held the highest market share of more than 55% in 2021 owing to the lack of internal expertise in the industry. This is attributed to their capabilities to add human-like post-translational modifications to complex protein therapeutics.

These developments have led to more productive and efficient manufacturing of biologics using mammalian cells. Non-mammalian cell lines, such as microbial cell lines, are recognized as potent factories. Innovative strategies are being implemented to identify and explore the potential of various microbes.

By Service Analysis

The contract research segment is expected to exhibit the fastest CAGR of 7.5% over the forecast period owing to the increasing outsourcing of research activities by biopharmaceutical companies.

These factors have resulted in the largest share of this segment. On the other hand, CROs are striving to capitalize on the potential avenues in the industry.

By Product Analysis

The biologics segment dominated the market with the largest revenue share of over 81% in 2021. This growth is attributed to the high specificity of biologics, complex manufacturing steps, and a higher success rate as compared to other drug molecules.

Several companies are investing in biosimilar development to outperform the safety, efficacy, disposition, or cost of earlier in-class innovator drugs. This has increased the level of competition amongst innovator manufacturers, which in turn, is likely to benefit the CMOs.

By Regional Analysis

North America held the largest revenue share of 33.97% in 2021. This can be attributed to the local presence of several service providers in the region. Also, a significant number of approved products in the U.S. are being manufactured by CMOs.

The key reason for the rise in outsourcing in Asian countries includes cost-associated benefits, such as lower labor costs and operating costs across the region.

Key Players

  • Boehringer Ingelheim GmbH
  • Lonza Group AG
  • Inno Biologics Sdn Bhd
  • Rentschler Biopharma SE
  • JRS Pharma
  • Biomeva GmbH
  • ProBioGen AG
  • Fujifilm Diosynth Biotechnologies U.S.A., Inc.
  • Toyobo Co., Ltd.
  • Samsung Biologics

Market Segmentation

  • By Source
    • Mammalian
    • Non-mammalian
  • By Service Type
    • Contract Manufacturing
      • Process Development
        • Downstream
        • Upstream
      • Fill & Finish Operations
      • Analytical & QC Studies
      • Packaging
    • Contract Research
      • Oncology
      • Inflammation & Immunology
      • Cardiology
      • Neuroscience
      • Others
  • By Product
    • Biologics
      • Monoclonal antibodies (MAbs)
      • Recombinant Proteins
      • Vaccines
      • Antisense, RNAi, & Molecular Therapy
      • Others
    • Biosimilars
  • Regional
    • North America
      • U.S.
      • Canada
    • Europe
      • Germany
      • France
    • Asia Pacific
      • China
      • India
    • Latin America
      • Brazil
    • Middle East & Africa
      • South Africa

Table of Contents

Chapter 1.  Introduction

1.1.  Research Objective

1.2.  Scope of the Study

1.3.  Definition

Chapter 2.  Research Methodology

2.1.  Research Approach

2.2.  Data Sources

2.3.  Assumptions & Limitations

Chapter 3.  Executive Summary

3.1.  Market Snapshot

Chapter 4.  Market Variables and Scope

4.1.  Introduction

4.2.  Market Classification and Scope

4.3.  Industry Value Chain Analysis

4.3.1.    Raw Material Procurement Analysis

4.3.2.    Sales and Distribution Channel Analysis

4.3.3.    Downstream Buyer Analysis

Chapter 5.  Market Dynamics Analysis and Trends

5.1.  Market Dynamics

5.1.1.    Market Drivers

5.1.2.    Market Restraints

5.1.3.    Market Opportunities

5.2.  Porter’s Five Forces Analysis

5.2.1.    Bargaining power of suppliers

5.2.2.    Bargaining power of buyers

5.2.3.    Threat of substitute

5.2.4.    Threat of new entrants

5.2.5.    Degree of competition

Chapter 6.  Competitive Landscape

6.1.1.    Company Market Share/Positioning Analysis

6.1.2.    Key Strategies Adopted by Players

6.1.3.    Vendor Landscape

6.1.3.1.        List of Suppliers

6.1.3.2.        List of Buyers

Chapter 7.  Global Biopharmaceutical CMO and CRO Market, By Source

7.1.  Biopharmaceutical CMO and CRO Market, by Source, 2021-2030

7.1.1.    Mammalian

7.1.1.1.        Market Revenue and Forecast (2017-2030)

7.1.2.    Non-mammalian

7.1.2.1.        Market Revenue and Forecast (2017-2030)

Chapter 8.  Global Biopharmaceutical CMO and CRO Market, By Service Type

8.1.  Biopharmaceutical CMO and CRO Market, by Service Type, 2021-2030

8.1.1.    Contract Manufacturing

8.1.1.1.        Market Revenue and Forecast (2017-2030)

8.1.2.    Contract Research

8.1.2.1.        Market Revenue and Forecast (2017-2030)

Chapter 9.  Global Biopharmaceutical CMO and CRO Market, By Product

9.1.  Biopharmaceutical CMO and CRO Market, by Product, 2021-2030

9.1.1.    Biologics

9.1.1.1.        Market Revenue and Forecast (2017-2030)

9.1.2.    Biosimilars

9.1.2.1.        Market Revenue and Forecast (2017-2030)

Chapter 10.      Global Biopharmaceutical CMO and CRO Market, Regional Estimates and Trend Forecast

10.1.        North America

10.1.1.  Market Revenue and Forecast, by Source (2017-2030)

10.1.2.  Market Revenue and Forecast, by Service Type (2017-2030)

10.1.3.  Market Revenue and Forecast, by Product (2017-2030)

10.1.4.  U.S.

10.1.4.1.      Market Revenue and Forecast, by Source (2017-2030)

10.1.4.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.1.4.3.      Market Revenue and Forecast, by Product (2017-2030)

10.1.5.  Rest of North America

10.1.5.1.      Market Revenue and Forecast, by Source (2017-2030)

10.1.5.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.1.5.3.      Market Revenue and Forecast, by Product (2017-2030)

10.2.        Europe

10.2.1.  Market Revenue and Forecast, by Source (2017-2030)

10.2.2.  Market Revenue and Forecast, by Service Type (2017-2030)

10.2.3.  Market Revenue and Forecast, by Product (2017-2030)

10.2.4.  UK

10.2.4.1.      Market Revenue and Forecast, by Source (2017-2030)

10.2.4.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.2.4.3.      Market Revenue and Forecast, by Product (2017-2030)

10.2.5.  Germany

10.2.5.1.      Market Revenue and Forecast, by Source (2017-2030)

10.2.5.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.2.5.3.      Market Revenue and Forecast, by Product (2017-2030)

10.2.6.  France

10.2.6.1.      Market Revenue and Forecast, by Source (2017-2030)

10.2.6.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.2.6.3.      Market Revenue and Forecast, by Product (2017-2030)

10.2.7.  Rest of Europe

10.2.7.1.      Market Revenue and Forecast, by Source (2017-2030)

10.2.7.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.2.7.3.      Market Revenue and Forecast, by Product (2017-2030)

10.3.        APAC

10.3.1.  Market Revenue and Forecast, by Source (2017-2030)

10.3.2.  Market Revenue and Forecast, by Service Type (2017-2030)

10.3.3.  Market Revenue and Forecast, by Product (2017-2030)

10.3.4.  India

10.3.4.1.      Market Revenue and Forecast, by Source (2017-2030)

10.3.4.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.3.4.3.      Market Revenue and Forecast, by Product (2017-2030)

10.3.5.  China

10.3.5.1.      Market Revenue and Forecast, by Source (2017-2030)

10.3.5.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.3.5.3.      Market Revenue and Forecast, by Product (2017-2030)

10.3.6.  Japan

10.3.6.1.      Market Revenue and Forecast, by Source (2017-2030)

10.3.6.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.3.6.3.      Market Revenue and Forecast, by Product (2017-2030)

10.3.7.  Rest of APAC

10.3.7.1.      Market Revenue and Forecast, by Source (2017-2030)

10.3.7.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.3.7.3.      Market Revenue and Forecast, by Product (2017-2030)

10.4.        MEA

10.4.1.  Market Revenue and Forecast, by Source (2017-2030)

10.4.2.  Market Revenue and Forecast, by Service Type (2017-2030)

10.4.3.  Market Revenue and Forecast, by Product (2017-2030)

10.4.4.  GCC

10.4.4.1.      Market Revenue and Forecast, by Source (2017-2030)

10.4.4.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.4.4.3.      Market Revenue and Forecast, by Product (2017-2030)

10.4.5.  North Africa

10.4.5.1.      Market Revenue and Forecast, by Source (2017-2030)

10.4.5.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.4.5.3.      Market Revenue and Forecast, by Product (2017-2030)

10.4.6.  South Africa

10.4.6.1.      Market Revenue and Forecast, by Source (2017-2030)

10.4.6.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.4.6.3.      Market Revenue and Forecast, by Product (2017-2030)

10.4.7.  Rest of MEA

10.4.7.1.      Market Revenue and Forecast, by Source (2017-2030)

10.4.7.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.4.7.3.      Market Revenue and Forecast, by Product (2017-2030)

10.5.        Latin America

10.5.1.  Market Revenue and Forecast, by Source (2017-2030)

10.5.2.  Market Revenue and Forecast, by Service Type (2017-2030)

10.5.3.  Market Revenue and Forecast, by Product (2017-2030)

10.5.4.  Brazil

10.5.4.1.      Market Revenue and Forecast, by Source (2017-2030)

10.5.4.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.5.4.3.      Market Revenue and Forecast, by Product (2017-2030)

10.5.5.  Rest of LATAM

10.5.5.1.      Market Revenue and Forecast, by Source (2017-2030)

10.5.5.2.      Market Revenue and Forecast, by Service Type (2017-2030)

10.5.5.3.      Market Revenue and Forecast, by Product (2017-2030)

Chapter 11.  Company Profiles

11.1.              Boehringer Ingelheim GmbH

11.1.1.  Company Overview

11.1.2.  Product Offerings

11.1.3.  Financial Performance

11.1.4.  Recent Initiatives

11.2.              Lonza Group AG

11.2.1.  Company Overview

11.2.2.  Product Offerings

11.2.3.  Financial Performance

11.2.4.  Recent Initiatives

11.3.              Inno Biologics Sdn Bhd

11.3.1.  Company Overview

11.3.2.  Product Offerings

11.3.3.  Financial Performance

11.3.4.  Recent Initiatives

11.4.              Rentschler Biopharma SE

11.4.1.  Company Overview

11.4.2.  Product Offerings

11.4.3.  Financial Performance

11.4.4.  Recent Initiatives

11.5.              JRS Pharma

11.5.1.  Company Overview

11.5.2.  Product Offerings

11.5.3.  Financial Performance

11.5.4.  Recent Initiatives

11.6.              Biomeva GmbH

11.6.1.  Company Overview

11.6.2.  Product Offerings

11.6.3.  Financial Performance

11.6.4.  Recent Initiatives

11.7.              ProBioGen AG

11.7.1.  Company Overview

11.7.2.  Product Offerings

11.7.3.  Financial Performance

11.7.4.  Recent Initiatives

11.8.              Fujifilm Diosynth Biotechnologies U.S.A., Inc.

11.8.1.  Company Overview

11.8.2.  Product Offerings

11.8.3.  Financial Performance

11.8.4.  Recent Initiatives

11.9.              Toyobo Co., Ltd.

11.9.1.  Company Overview

11.9.2.  Product Offerings

11.9.3.  Financial Performance

11.9.4.  Recent Initiatives

11.10.           Samsung Biologics

11.10.1.               Company Overview

11.10.2.               Product Offerings

11.10.3.               Financial Performance

11.10.4.               Recent Initiatives

Chapter 12.  Research Methodology

12.1.              Primary Research

12.2.              Secondary Research

12.3.              Assumptions

Chapter 13.  Appendix

13.1.              About Us

13.2.              Glossary of Terms

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